Flight tickets from Chicago Midway to Guayaquil

How to find cheap flights to Guayaquil (GYE) from Chicago (MDW) in 2026

Looking for cheap tickets from Chicago Midway to Guayaquil? Return tickets start from ₹ 52,657 and one-way flights to Guayaquil from Chicago Midway start from ₹ 20,954

Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

• Simply hit 'search'. From British Airways to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets from Chicago Midway to Guayaquil. And with us there are no hidden fees - what you see is what you pay.
• Compare flight deals to Guayaquil from Chicago from over 1,000 providers. Then choose the cheapest or fastest plane tickets. Flight tickets to Guayaquil start from ₹ 20,954 one-way.
• Flex your dates to find the best MDW-GYE ticket prices. If you are flexible when it comes to your travel dates, use Skyscanner's 'Whole month' tool to find the cheapest month, and even day to fly to Guayaquil from Chicago Midway.
• Set up a Price Alert. You can easily track the fare of your cheap Chicago Midway-Guayaquil flights by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.
• Find the cheapest Business class flights from Chicago Midway and Guayaquil. We scour the internet for the best Business, Premium Economy and First Class flight fares to Guayaquil, too. Check the difference in price as you search – you might just chance upon a last-minute low fare. Note that not all cabin classes are available for every destination or airline.
• Include nearby airports in your search. Widen your search for Chicago Midway to Guayaquil flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save next time you travel.
• Search for cheap flights regardless of where you are. To get the best flight booking experience when out and about, download the app and search for plane tickets between Chicago Midway and Guayaquil whenever you want.

Combine your flight to Guayaquil from Chicago Midway with hotels and car hire

Once you've secured your cheap flight ticket from Chicago Midway to Guayaquil, discover the best prices and exclusive rates for hotels in Guayaquil or nearby. You can also compare hundreds of car hire companies in one go so that you get the best car hire price for your trip.