Flight tickets from Knoxville (TYS) to Santiago (STI) from ₹ 37,929

How to find cheap flights to Santiago (STI) from Knoxville (TYS) in 2026

Looking for cheap tickets from Knoxville to Santiago? Return tickets start from ₹ 59,008 and one-way flights to Santiago from Knoxville start from ₹ 37,929

Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

• Simply hit 'search'. From British Airways to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets from Knoxville to Santiago. And with us there are no hidden fees - what you see is what you pay.
• Compare flight deals to Santiago from Knoxville from over 1,000 providers. Then choose the cheapest or fastest plane tickets. Flight tickets to Santiago start from ₹ 37,929 one-way.
• Flex your dates to find the best TYS-STI ticket prices. If you are flexible when it comes to your travel dates, use Skyscanner's 'Whole month' tool to find the cheapest month, and even day to fly to Santiago from Knoxville.
• Set up a Price Alert. You can easily track the fare of your cheap Knoxville-Santiago flights by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.
• Find the cheapest Business class flights from Knoxville and Santiago. We scour the internet for the best Business, Premium Economy and First Class flight fares to Santiago, too. Check the difference in price as you search – you might just chance upon a last-minute low fare. Note that not all cabin classes are available for every destination or airline.
• Include nearby airports in your search. Widen your search for Knoxville to Santiago flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save next time you travel.
• Search for cheap flights regardless of where you are. To get the best flight booking experience when out and about, download the app and search for plane tickets between Knoxville and Santiago whenever you want.

Combine your flight to Santiago from Knoxville with hotels and car hire

Once you've secured your cheap flight ticket from Knoxville to Santiago, discover the best prices and exclusive rates for hotels in Santiago or nearby. You can also compare hundreds of car hire companies in one go so that you get the best car hire price for your trip.